Crestor

The popular cholesterol-lowering drug Crestor (Rosuvastatin) poses a greater risk of renal failure and serious adverse muscle effects which can cause liver damage and failure, kidney damage and failure, other organ failure and even death. Patients with a greater risk are those who have hypothyroidism and/or renal insufficiency as well as patients who are of Chinese or Japanese descent.

Crestor, commonly referred to as a statin, was developed by AstraZeneca, and is based on a compound discovered by a Japanese pharmaceutical company, Shionogi. Statins, such as Crestor, lower "bad" cholesterol and triglycerides and raise "good" cholesterol in the blood.

Serious side effects may include liver damage, liver failure, severe muscle damage/deterioration, kidney failure, kidney damage, other organ failure and/or death. Physical signs or symptoms of adverse reactions include but are not limited to muscle weakness, muscle tenderness, malaise, fever, dark urine, nausea or vomiting.

A consumer group, Public Citizen, filed a petition March 2004 with the FDA to remove the drug from the market. Dr. Sidney Wolfe, director of Public Citizen's Health Research Group stated to FDA Acting Commissioner Lester Crawford: "It becomes clearer by the day that this drug is uniquely toxic and offers no unique benefit, and must be removed from the market."

Dr. David Graham, associate director for science and medicine in the FDA's Office of Drug Safety, testified November 18, 2004, before a House Committee Hearing regarding the FDA's handling of the removal of Merck's Vioxx from the market for safety reasons. Dr. Graham said the agency should take a serious look at the recently approved Crestor, which he said appears to have a risk of renal failure. He pointed out that there are already a number of other drugs in Crestor's class on the market that do not pose such a risk.

If you or a loved one have experienced any side effects from Crestor, including liver failure, liver damage, kidney failure, kidney damage, other organ failure and/or death or severe muscle damage/deterioration, please call us at 1.800.966.4999 or fill out the form to the right of the page for immediate attention to your case.

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